Biomarkers of Good EULAR Response to the B Cell Depletion Therapy in All Seropositive Rheumatoid Arthritis Patients: Clues for the Pathogenesis

Gianfranco Ferraccioli; Barbara Tolusso; F Bobbio Pallavicini; Elisa Gremese; V Ravagnani; M Benucci; E Podestà; F Atzeni; Alice Mannocci; D Biasi; Marina Manfredi; P Sarzi Puttini; B Laganà; C. Montecucco

doi:10.1371/journal.pone.0040362

Biomarkers of Good EULAR Response to the B Cell Depletion Therapy in All Seropositive Rheumatoid Arthritis Patients: Clues for the Pathogenesis

Gianfranco Ferraccioli^*
, Barbara Tolusso
, F Bobbio Pallavicini
, Elisa Gremese
, V Ravagnani
, M Benucci
, E Podestà
, F Atzeni
, Alice Mannocci
, D Biasi
, Marina Manfredi
, P Sarzi Puttini
, B Laganà
, C. Montecucco

^*Corresponding author

Faculty of Medicine and Surgery

Sapienza University

Research output: Contribution to journal › Article

27 Citations (Scopus)

Abstract

To find out whether a high number of auto-antibodies can increase the probability of a "good-EULAR response" and to identify the possible biomarkers of response in seropositive rheumatoid arthritis (RA) patients undergoing the B cell depletion therapy (BCDT).

Original language	English
Pages (from-to)	e40362-e40369
Number of pages	7
Journal	PLoS One
Volume	7
Issue number	7
DOIs	https://doi.org/10.1371/journal.pone.0040362
Publication status	Published - 2012

All Science Journal Classification (ASJC) codes

General

Keywords

B cells
rheumatoid arthritis

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10.1371/journal.pone.0040362

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Ferraccioli, G., Tolusso, B., Bobbio Pallavicini, F., Gremese, E., Ravagnani, V., Benucci, M., Podestà, E., Atzeni, F., Mannocci, A., Biasi, D., Manfredi, M., Sarzi Puttini, P., Laganà, B., & Montecucco, C. (2012). Biomarkers of Good EULAR Response to the B Cell Depletion Therapy in All Seropositive Rheumatoid Arthritis Patients: Clues for the Pathogenesis. PLoS One, 7(7), e40362-e40369. https://doi.org/10.1371/journal.pone.0040362

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abstract = "To find out whether a high number of auto-antibodies can increase the probability of a {"}good-EULAR response{"} and to identify the possible biomarkers of response in seropositive rheumatoid arthritis (RA) patients undergoing the B cell depletion therapy (BCDT).",

keywords = "B cells, rheumatoid arthritis, B cells, rheumatoid arthritis",

author = "Gianfranco Ferraccioli and Barbara Tolusso and \{Bobbio Pallavicini\}, F and Elisa Gremese and V Ravagnani and M Benucci and E Podest{\`a} and F Atzeni and Alice Mannocci and D Biasi and Marina Manfredi and \{Sarzi Puttini\}, P and B Lagan{\`a} and C. Montecucco",

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Ferraccioli, G, Tolusso, B, Bobbio Pallavicini, F, Gremese, E, Ravagnani, V, Benucci, M, Podestà, E, Atzeni, F, Mannocci, A, Biasi, D, Manfredi, M, Sarzi Puttini, P, Laganà, B & Montecucco, C 2012, 'Biomarkers of Good EULAR Response to the B Cell Depletion Therapy in All Seropositive Rheumatoid Arthritis Patients: Clues for the Pathogenesis', PLoS One, vol. 7, no. 7, pp. e40362-e40369. https://doi.org/10.1371/journal.pone.0040362

TY - JOUR

T1 - Biomarkers of Good EULAR Response to the B Cell Depletion Therapy in All Seropositive Rheumatoid Arthritis Patients: Clues for the Pathogenesis

AU - Ferraccioli, Gianfranco

AU - Tolusso, Barbara

AU - Bobbio Pallavicini, F

AU - Gremese, Elisa

AU - Ravagnani, V

AU - Benucci, M

AU - Podestà, E

AU - Atzeni, F

AU - Mannocci, Alice

AU - Biasi, D

AU - Manfredi, Marina

AU - Sarzi Puttini, P

AU - Laganà, B

AU - Montecucco, C.

PY - 2012

Y1 - 2012

N2 - To find out whether a high number of auto-antibodies can increase the probability of a "good-EULAR response" and to identify the possible biomarkers of response in seropositive rheumatoid arthritis (RA) patients undergoing the B cell depletion therapy (BCDT).

AB - To find out whether a high number of auto-antibodies can increase the probability of a "good-EULAR response" and to identify the possible biomarkers of response in seropositive rheumatoid arthritis (RA) patients undergoing the B cell depletion therapy (BCDT).

KW - B cells

KW - rheumatoid arthritis

KW - B cells

KW - rheumatoid arthritis

UR - https://publicatt.unicatt.it/handle/10807/31456

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U2 - 10.1371/journal.pone.0040362

DO - 10.1371/journal.pone.0040362

M3 - Article

SN - 1932-6203

VL - 7

SP - e40362-e40369

JO - PLoS One

JF - PLoS One

IS - 7

ER -

Biomarkers of Good EULAR Response to the B Cell Depletion Therapy in All Seropositive Rheumatoid Arthritis Patients: Clues for the Pathogenesis

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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