Beneficial therapeutic effects of vitamin C on recurrent respiratory tract infections in children: preliminary data

Pietro Ferrara; Francesca Ianniello; Virginia Bianchi; Fabio Quintarelli; Michela Cammerata; Enrica Quattrocchi; Gloria M. Terranova; Giacinto Abele Donato Miggiano; Manuele Casale

doi:10.23736/S2724-5276.16.04621-1

Beneficial therapeutic effects of vitamin C on recurrent respiratory tract infections in children: preliminary data

Pietro Ferrara, Francesca Ianniello, Virginia Bianchi, Fabio Quintarelli, Michela Cammerata, Enrica Quattrocchi, Gloria M. Terranova, Giacinto Abele Donato Miggiano, Manuele Casale

Università Cattolica del Sacro Cuore

Universita Campus Bio-Medico di Roma

Research output: Contribution to journal › Article

Abstract

BACKGROUND: To demonstrate whether supplementation of vitamin C has a beneficial effect in the prevention of recurrent respiratory tract infections (RTIs) in children. Moreover, we evaluate the main risk factors that predispose to the development of this disease. METHODS: Sixty children have been enrolled in the study and randomized into two groups: the control group (G1 n = 33) and the group at risk of recurrent RTIs (G2 n = 27). To G2 group was administered every day 100% orange juice with the content of vitamin C 70 mg. RESULTS: Significant reduction in the incidence rate of RTIs (episodes pre-treatment: 182-6.75 episodes/child, after-treatment: 71-2.62 episodes/child, P <0.05), were observed in G2 group. CONCLUSIONS: The administration of vitamin C had a beneficial effect in our group of children with recurrent RTIs, reducing the number of infective episodes.

Original language	English
Pages (from-to)	N/A-N/A
Journal	Minerva Pediatrica
DOIs	https://doi.org/10.23736/S2724-5276.16.04621-1
Publication status	Published - 2016

Keywords

child

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10.23736/S2724-5276.16.04621-1

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@article{073a30652e514b2589a5a4870babcb94,

title = "Beneficial therapeutic effects of vitamin C on recurrent respiratory tract infections in children: preliminary data",

abstract = "BACKGROUND: To demonstrate whether supplementation of vitamin C has a beneficial effect in the prevention of recurrent respiratory tract infections (RTIs) in children. Moreover, we evaluate the main risk factors that predispose to the development of this disease. METHODS: Sixty children have been enrolled in the study and randomized into two groups: the control group (G1 n = 33) and the group at risk of recurrent RTIs (G2 n = 27). To G2 group was administered every day 100% orange juice with the content of vitamin C 70 mg. RESULTS: Significant reduction in the incidence rate of RTIs (episodes pre-treatment: 182-6.75 episodes/child, after-treatment: 71-2.62 episodes/child, P <0.05), were observed in G2 group. CONCLUSIONS: The administration of vitamin C had a beneficial effect in our group of children with recurrent RTIs, reducing the number of infective episodes.",

keywords = "child, child",

author = "Pietro Ferrara and Francesca Ianniello and Virginia Bianchi and Fabio Quintarelli and Michela Cammerata and Enrica Quattrocchi and Terranova, {Gloria M.} and Miggiano, {Giacinto Abele Donato} and Manuele Casale",

year = "2016",

doi = "10.23736/S2724-5276.16.04621-1",

language = "English",

pages = "N/A--N/A",

journal = "Policlinico infantile",

issn = "0026-4946",

publisher = "Edizioni Minerva Medica:Corso Bramante 83-85, 10126 Turin Italy:011 39 011 678282318, EMAIL: journals.dept@minervamedica.it, INTERNET: http://www.minervamedica.it, Fax: 011 39 011 674502",

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TY - JOUR

T1 - Beneficial therapeutic effects of vitamin C on recurrent respiratory tract infections in children: preliminary data

AU - Ferrara, Pietro

AU - Ianniello, Francesca

AU - Bianchi, Virginia

AU - Quintarelli, Fabio

AU - Cammerata, Michela

AU - Quattrocchi, Enrica

AU - Terranova, Gloria M.

AU - Miggiano, Giacinto Abele Donato

AU - Casale, Manuele

PY - 2016

Y1 - 2016

N2 - BACKGROUND: To demonstrate whether supplementation of vitamin C has a beneficial effect in the prevention of recurrent respiratory tract infections (RTIs) in children. Moreover, we evaluate the main risk factors that predispose to the development of this disease. METHODS: Sixty children have been enrolled in the study and randomized into two groups: the control group (G1 n = 33) and the group at risk of recurrent RTIs (G2 n = 27). To G2 group was administered every day 100% orange juice with the content of vitamin C 70 mg. RESULTS: Significant reduction in the incidence rate of RTIs (episodes pre-treatment: 182-6.75 episodes/child, after-treatment: 71-2.62 episodes/child, P <0.05), were observed in G2 group. CONCLUSIONS: The administration of vitamin C had a beneficial effect in our group of children with recurrent RTIs, reducing the number of infective episodes.

AB - BACKGROUND: To demonstrate whether supplementation of vitamin C has a beneficial effect in the prevention of recurrent respiratory tract infections (RTIs) in children. Moreover, we evaluate the main risk factors that predispose to the development of this disease. METHODS: Sixty children have been enrolled in the study and randomized into two groups: the control group (G1 n = 33) and the group at risk of recurrent RTIs (G2 n = 27). To G2 group was administered every day 100% orange juice with the content of vitamin C 70 mg. RESULTS: Significant reduction in the incidence rate of RTIs (episodes pre-treatment: 182-6.75 episodes/child, after-treatment: 71-2.62 episodes/child, P <0.05), were observed in G2 group. CONCLUSIONS: The administration of vitamin C had a beneficial effect in our group of children with recurrent RTIs, reducing the number of infective episodes.

KW - child

UR - http://hdl.handle.net/10807/90059

U2 - 10.23736/S2724-5276.16.04621-1

DO - 10.23736/S2724-5276.16.04621-1

M3 - Article

SN - 0026-4946

SP - N/A-N/A

JO - Policlinico infantile

JF - Policlinico infantile

ER -

Beneficial therapeutic effects of vitamin C on recurrent respiratory tract infections in children: preliminary data

Abstract

Keywords

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