Bariatric surgery versus conventional medical therapy for type 2 diabetes

Geltrude Mingrone, Simona Panunzi, Andrea De Gaetano, Caterina Guidone, Amerigo Iaconelli, Laura Leccesi, Giuseppe Nanni, Marco Castagneto, Giovanni Ghirlanda, Francesco Rubino, Alfons Pomp

Research output: Contribution to journalArticle

1220 Citations (Scopus)


Roux-en-Y gastric bypass and biliopancreatic diversion can markedly ameliorate diabetes in morbidly obese patients, often resulting in disease remission. Prospective, randomized trials comparing these procedures with medical therapy for the treatment of diabetes are needed.
Original languageEnglish
Pages (from-to)1577-1585
Number of pages9
JournalNew England Journal of Medicine
Publication statusPublished - 2012


  • Adult
  • Analysis of Variance
  • Biliopancreatic Diversion
  • Body Mass Index
  • Diabetes Mellitus, Type 2
  • Female
  • Follow-Up Studies
  • Gastric Bypass
  • Hemoglobin A, Glycosylated
  • Humans
  • Hypoglycemic Agents
  • Insulin
  • Lipids
  • Male
  • Middle Aged
  • Obesity, Morbid
  • Remission Induction
  • Weight Loss


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