Autologous peripheral blood stem cell transplantation and the role of lenalidomide in patients affected by poems syndrome

Nicola Piccirillo, Federica Sora', Patrizia Chiusolo, Simona Sica, Luca Laurenti, Francesco Autore, Idanna Innocenti, Marco Luigetti, Andrea Bacigalupo

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

POEMS syndrome is a rare paraneoplastic condition, with a poorly understood pathogenesis. High dose chemotherapy followed by autologous stem cell transplantation (ASCT) has been reported to be an effective therapeutic option for patients with good performance status. Here, we review the role of ASCT for POEMS syndrome and discuss indications together with advantages and disadvantages, and related issues such lenalidomide given before or after ASCT, VEGF levels as a marker of disease, and different regimens for stem cell mobilization.
Original languageEnglish
Pages (from-to)2478-2483
Number of pages6
JournalHematological Oncology
DOIs
Publication statusPublished - 2017

Keywords

  • ASCT
  • Cancer Research
  • Hematology
  • Lenalidomide
  • Oncology
  • Poems

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