Atypical carcinoid and large cell neuroendocrine carcinoma of the lung: A proteomic dataset from formalin-fixed archival samples

Guido Rindi, Alessandro Tanca, Maria Filippa Addis, Salvatore Pisanu, Marcello Abbondio, Daniela Pagnozzi, Albino Eccher, Paolo Cossu-Rocca, Sergio Uzzau, Giuseppe Fanciulli

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Here we present a dataset generated using formalin-fixed paraffin-embedded archival samples from two rare lung neuroendocrine tumor subtypes (namely, two atypical carcinoids, ACs, and two large-cell neuroendocrine carcinomas, LCNECs). Samples were subjected to a shotgun proteomics pipeline, comprising full-length protein extraction, SDS removal through spin columns, in solution trypsin digestion, long gradient liquid chromatography peptide separation and LTQ-Orbitrap mass spectrometry analysis. A total of 1260 and 2436 proteins were identified in the AC and LCNEC samples, respectively, with FDR <1%. MS data are available in the PeptideAtlas repository at http://www.peptideatlas.org/PASS/PASS00375.
Original languageEnglish
Pages (from-to)529-531
Number of pages3
JournalData in Brief
Volume7
DOIs
Publication statusPublished - 2016

Keywords

  • 3304
  • Archival tissues
  • FFPE
  • Mass spectrometry
  • Multidisciplinary
  • Neuroendocrine tumors
  • Proteomics

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