[Autom. eng. transl.] OBJECTIVES: Knowing the needs for care and health is an essential element for health planning. This pilot study, conducted in Campania, investigates the diagnostic-therapeutic pathways and the demographic and clinical characteristics of patients suffering from multiple sclerosis (MS). METHOD: In 2011 a survey was conducted at all the Campanian reference centers for MS with reference to the activity data for the March-August semester. The Centers were asked to answer, through a dedicated Web portal, a questionnaire of 30 questions on demographic, clinical and care aspects of their patients. RESULTS: In the 6 months of the study 3263 patients (average age 37 years, 66% females) made at least one access to the Centers; for 293 of these (9.0%) this access was the first ever. 5.7% of patients were resident in regions other than Campania. They received a first diagnosis of MS 161 (4.9%) subjects. Of the referrals to the Centers without previous diagnosis, access was made on their own initiative in 37.3% of cases, in the emergency room in 7.9%, at the suggestion of the attending physician in 17.8% and on the advice of the specialist in 37, 1%. Disease onset occurred in 72% of cases between 20 and 39 years. The most common symptoms / signs at onset were: visual acuity disorders / scotomas (53.9%), dysesthesia (50.2%), fatigue (40.3%), reduction in strength / muscle tone (39 , 9%). All patients underwent a complete neurological objective examination and Expanded Disability Status Scale. Other commonly performed investigations were MRI (44.0%), evoked potentials (22.1%) and ophthalmological evaluation (15.0%). 2797 (87.1%) subjects were treated, of whom 235 (7.2% of the total) were naive. The most commonly used drugs were Interferon ß and Glatiramer acetate. The time elapsed between diagnosis and initiation of therapy has exceeded 6 months in 32% of cases. 140 (5% of the treaties) have changed therapeutic regimen (63% for intolerance, 33% for ineffectiveness, 4% for poor compliance); of the 40 who stopped treatment (1.4% of the treaties) 32% did so due to intolerance, 20% due to ineffectiveness, 25% due to pregnancy and 23% for other reasons. CONCLUSIONS: The results of the Campania Region are essentially in line with the national ones. The methods of presentation to the MS Centers and the delay in the start of therapy, established for some patients, could however indicate margins for improvement in the care network. The results also show a sub-utilization of second-line drugs which, however, deserves further investigation also with a view to inter-regional comparison.
|Translated title of the contribution||[Autom. eng. transl.] Clinical-care aspects of multiple sclerosis in Campania: results of a survey conducted at the reference centers.|
|Number of pages||2|
|Journal||ANNALI DI IGIENE MEDICINA PREVENTIVA E DI COMUNITÀ|
|Publication status||Published - 2013|
|Event||45° Congresso Nazionale SItI - Cagliari|
Duration: 3 Oct 2012 → 6 Oct 2012