Antiplatelet agents for the treatment and prevention of atherothrombosis

Carlo Patrono, Felicita Andreotti, H Arnesen, L Badimon, C Baigent, J Collet, R De Caterina, D Gulba, K Huber, S Husted, Sd Kristensen, J Morais, F Neumann, Lh Rasmussen, A Siegbahn, P Steg, Rf Storey, F Van De Werf, F. Verheugt

Research output: Contribution to journalArticle

174 Citations (Scopus)

Abstract

The clinical pharmacology of antiplatelet drugs has been reviewed previously by the European Society of Cardiology (ESC) Task force and by the 8th American College of Chest Physicians (ACCP) Evidence-Based Clinical Practice Guidelines. Moreover, information on the efficacy and safety of antiplatelet drugs in the treatment and prevention of atherothrombosis is provided by collaborative meta-analyses of 287 secondary prevention trials and 6 primary prevention trials. The present document intends to provide practicing physicians with an updated instrument to guide their choice of the most suitable antiplatelet strategy for the individual patient at risk, or with different clinical manifestations, of atherothrombosis.
Original languageEnglish
Pages (from-to)2922-2932
Number of pages11
JournalEuropean Heart Journal
Volume32
DOIs
Publication statusPublished - 2011

Keywords

  • Coronary Artery Disease
  • Coronary Thrombosis
  • Drug Therapy, Combination
  • Humans
  • Platelet Activation
  • Platelet Aggregation Inhibitors
  • Risk Factors

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