Antimicrobial-resistant Gram-negative bacteria in febrile neutropenic patients with cancer: current epidemiology and clinical impact

Enrico Maria Trecarichi; Mario Tumbarello

doi:10.1097/QCO.0000000000000038

Antimicrobial-resistant Gram-negative bacteria in febrile neutropenic patients with cancer: current epidemiology and clinical impact

Enrico Maria Trecarichi, Mario Tumbarello

Università Cattolica del Sacro Cuore

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67 Citations (Scopus)

Abstract

In the recent years, several studies involving cancer patients have demonstrated a clear trend in the epidemiology of bacterial infections showing a shift in the prevalence from Gram-positive to Gram-negative bacteria and the extensive emergence of antimicrobial-resistant strains among Gram-negatives isolated from the blood. The aim of this systematic review was to examine the recent trends in epidemiology and antimicrobial resistance in Gram-negatives recovered from neutropenic cancer patients, with particular emphasis on the impact of antimicrobial resistance on the clinical outcome of severe infections caused by such microorganisms.

Original language	English
Pages (from-to)	200-210
Number of pages	11
Journal	Current Opinion in Infectious Diseases
Volume	27
DOIs	https://doi.org/10.1097/QCO.0000000000000038
Publication status	Published - 2014

Keywords

Anti-Bacterial Agents
Drug Resistance, Bacterial
Febrile Neutropenia
Gram-Negative Bacteria
Gram-Negative Bacterial Infections
Humans
Neoplasms

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1097/QCO.0000000000000038

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abstract = "In the recent years, several studies involving cancer patients have demonstrated a clear trend in the epidemiology of bacterial infections showing a shift in the prevalence from Gram-positive to Gram-negative bacteria and the extensive emergence of antimicrobial-resistant strains among Gram-negatives isolated from the blood. The aim of this systematic review was to examine the recent trends in epidemiology and antimicrobial resistance in Gram-negatives recovered from neutropenic cancer patients, with particular emphasis on the impact of antimicrobial resistance on the clinical outcome of severe infections caused by such microorganisms.",

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AU - Trecarichi, Enrico Maria

AU - Tumbarello, Mario

PY - 2014

Y1 - 2014

N2 - In the recent years, several studies involving cancer patients have demonstrated a clear trend in the epidemiology of bacterial infections showing a shift in the prevalence from Gram-positive to Gram-negative bacteria and the extensive emergence of antimicrobial-resistant strains among Gram-negatives isolated from the blood. The aim of this systematic review was to examine the recent trends in epidemiology and antimicrobial resistance in Gram-negatives recovered from neutropenic cancer patients, with particular emphasis on the impact of antimicrobial resistance on the clinical outcome of severe infections caused by such microorganisms.

AB - In the recent years, several studies involving cancer patients have demonstrated a clear trend in the epidemiology of bacterial infections showing a shift in the prevalence from Gram-positive to Gram-negative bacteria and the extensive emergence of antimicrobial-resistant strains among Gram-negatives isolated from the blood. The aim of this systematic review was to examine the recent trends in epidemiology and antimicrobial resistance in Gram-negatives recovered from neutropenic cancer patients, with particular emphasis on the impact of antimicrobial resistance on the clinical outcome of severe infections caused by such microorganisms.

KW - Anti-Bacterial Agents

KW - Drug Resistance, Bacterial

KW - Febrile Neutropenia

KW - Gram-Negative Bacteria

KW - Gram-Negative Bacterial Infections

KW - Humans

KW - Neoplasms

KW - Anti-Bacterial Agents

KW - Drug Resistance, Bacterial

KW - Febrile Neutropenia

KW - Gram-Negative Bacteria

KW - Gram-Negative Bacterial Infections

KW - Humans

KW - Neoplasms

UR - http://hdl.handle.net/10807/65017

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DO - 10.1097/QCO.0000000000000038

M3 - Article

SN - 0951-7375

VL - 27

SP - 200

EP - 210

JO - Current Opinion in Infectious Diseases

JF - Current Opinion in Infectious Diseases

ER -

Antimicrobial-resistant Gram-negative bacteria in febrile neutropenic patients with cancer: current epidemiology and clinical impact

Abstract

Keywords

UN SDGs

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