Anti-TNF-α-induced psoriasiform lesions in IBD: An abnormal immune activation or a 'patchy cutaneous' immune suppression?

Franco Scaldaferri, Valentina Petito, Alfredo Papa, Monica Cesarini, Vincenzo Arena, Loris Riccardo Lopetuso, Maddalena Corbi, Francesca Perino, Giacomo Caldarola, Angelo Carbone, Enrico Corazziari, Alessandro Sgambato, Antonio Gasbarrini, Clara De Simone

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Our case suggests that some form of psoriasiform or psoriasis-like lesions could be associated with a decrease in chemokines and inflammatory cytokines compard with healthy skin, with regulatory prevailing on pro-inflammatory mechanisms.
Original languageEnglish
Pages (from-to)699-701
Number of pages3
JournalGut
Volume63
DOIs
Publication statusPublished - 2014

Keywords

  • Antibodies
  • Crohn's Disease
  • Drug Toxicity
  • Female
  • Gastroenterology
  • Humans
  • IBD Basic Research
  • Immunology
  • Inflammatory Bowel Diseases
  • Interferon-gamma
  • Interleukin-12
  • Interleukin-17
  • Interleukin-23
  • Interleukins
  • Male
  • Psoriasis
  • Th1 Cells
  • Tumor Necrosis Factor-alpha

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