Anti-MuSK antibodies: Correlation with myasthenia gravis severity

Emanuela Bartoccioni; Flavia Scuderi; Giacomo Maria Minicuci; Mariapaola Marino; F. Ciaraffa; Amelia Evoli Stampanoni-B

doi:10.1212/01.wnl.0000228225.23349.5d

Anti-MuSK antibodies: Correlation with myasthenia gravis severity

Emanuela Bartoccioni
, Flavia Scuderi
, Giacomo Maria Minicuci
, Mariapaola Marino
, F. Ciaraffa
, Amelia Evoli Stampanoni-B^*

^*Corresponding author

Research output: Contribution to journal › Article

100 Citations (Scopus)

Abstract

The authors measured anti–muscle-specific tyrosine kinase (anti- MuSK) antibodies (Abs) in 83 serum samples from 40 patients and evaluated their correlation with myasthenia gravis severity and treatment response. Ab concentrations were often reduced by immunosuppression but not after thymectomy. Both in individual cases and in the whole population, a correlation between Ab levels and disease severity was found.

Original language	English
Pages (from-to)	505-507
Number of pages	3
Journal	Neurology
Volume	67
DOIs	https://doi.org/10.1212/01.wnl.0000228225.23349.5d
Publication status	Published - 2006

Keywords

Adolescent
Adult
Aged
Antibodies
Child
Female
Humans
Male
Middle Aged
Myasthenia Gravis
Receptor Protein-Tyrosine Kinases
Receptors, Cholinergic
Severity of Illness Index
Statistics as Topic

Access to Document

10.1212/01.wnl.0000228225.23349.5d

Cite this

@article{ce4436e395bb4c0482e53a4b11d690aa,

title = "Anti-MuSK antibodies: Correlation with myasthenia gravis severity",

abstract = "The authors measured anti{\textendash}muscle-specific tyrosine kinase (anti- MuSK) antibodies (Abs) in 83 serum samples from 40 patients and evaluated their correlation with myasthenia gravis severity and treatment response. Ab concentrations were often reduced by immunosuppression but not after thymectomy. Both in individual cases and in the whole population, a correlation between Ab levels and disease severity was found.",

keywords = "Adolescent, Adult, Aged, Antibodies, Child, Female, Humans, Male, Middle Aged, Myasthenia Gravis, Receptor Protein-Tyrosine Kinases, Receptors, Cholinergic, Severity of Illness Index, Statistics as Topic, Adolescent, Adult, Aged, Antibodies, Child, Female, Humans, Male, Middle Aged, Myasthenia Gravis, Receptor Protein-Tyrosine Kinases, Receptors, Cholinergic, Severity of Illness Index, Statistics as Topic",

author = "Emanuela Bartoccioni and Flavia Scuderi and Minicuci, \{Giacomo Maria\} and Mariapaola Marino and F. Ciaraffa and \{Evoli Stampanoni-B\}, Amelia",

year = "2006",

doi = "10.1212/01.wnl.0000228225.23349.5d",

language = "English",

volume = "67",

pages = "505--507",

journal = "Neurology",

issn = "0028-3878",

publisher = "Lippincott Williams and Wilkins",

}

TY - JOUR

T1 - Anti-MuSK antibodies: Correlation with myasthenia gravis severity

AU - Bartoccioni, Emanuela

AU - Scuderi, Flavia

AU - Minicuci, Giacomo Maria

AU - Marino, Mariapaola

AU - Ciaraffa, F.

AU - Evoli Stampanoni-B, Amelia

PY - 2006

Y1 - 2006

N2 - The authors measured anti–muscle-specific tyrosine kinase (anti- MuSK) antibodies (Abs) in 83 serum samples from 40 patients and evaluated their correlation with myasthenia gravis severity and treatment response. Ab concentrations were often reduced by immunosuppression but not after thymectomy. Both in individual cases and in the whole population, a correlation between Ab levels and disease severity was found.

AB - The authors measured anti–muscle-specific tyrosine kinase (anti- MuSK) antibodies (Abs) in 83 serum samples from 40 patients and evaluated their correlation with myasthenia gravis severity and treatment response. Ab concentrations were often reduced by immunosuppression but not after thymectomy. Both in individual cases and in the whole population, a correlation between Ab levels and disease severity was found.

KW - Adolescent

KW - Adult

KW - Aged

KW - Antibodies

KW - Child

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Myasthenia Gravis

KW - Receptor Protein-Tyrosine Kinases

KW - Receptors, Cholinergic

KW - Severity of Illness Index

KW - Statistics as Topic

KW - Adolescent

KW - Adult

KW - Aged

KW - Antibodies

KW - Child

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Myasthenia Gravis

KW - Receptor Protein-Tyrosine Kinases

KW - Receptors, Cholinergic

KW - Severity of Illness Index

KW - Statistics as Topic

UR - http://hdl.handle.net/10807/163601

U2 - 10.1212/01.wnl.0000228225.23349.5d

DO - 10.1212/01.wnl.0000228225.23349.5d

M3 - Article

SN - 0028-3878

VL - 67

SP - 505

EP - 507

JO - Neurology

JF - Neurology

ER -

Anti-MuSK antibodies: Correlation with myasthenia gravis severity

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this