Analisi del contesto di applicazione della tecnologia

Translated title of the contribution: [Autom. eng. transl.] Analysis of the context of application of technology

Chiara Cadeddu, Gualtiero Ricciardi, Chiara De Waure, Francesco Di Nardo, Antonella Sferrazza, Nicola Nicolotti, Maria Rosaria Gualano, Giuseppe La Torre, F Lombardo, A Lenzi

Research output: Contribution to journalArticle


[Autom. eng. transl.] Infertility, understood as an inability to conceive after a year of sexual relations without the adoption of contraceptive measures, affects 3.5 to 16.7% of couples in developed countries: around one in 10 couples therefore turns to the doctor because of problems of infertility. Contributing to the problem we find both female and male causes, although in 5-15% of cases sterility remains of unknown origin. The most frequent of the female causes involving anovulatory age is represented by polycystic ovary syndrome, which can affect up to 1 in 7 women and is responsible for 70% of cases of infertility. Among the male causes, primary testicular failure contributes to 75% of cases of infertility. Advanced age, alcohol intake, smoking habits and excessively high or reduced body weight are also factors that can influence fertility. The approach to the sterile couple provides a path to different stages with first-level exams and general recommendations which can be followed by second-level assessments and reference to the Centers offering Medically Assisted Procreation (PMA) services. Access to MAP centers has progressively increased over the years (from 46,519 couples treated in 2005 to 63,840 in 2009); in 2009, 20,315 couples resorted to first-level techniques (simple insemination) and 39,761 couples to second and third level techniques. PMA techniques involve the initiation of multiple follicular growth induction protocols (ICFM) in which FSH, LH and GnRH agonist analogues are generally used. ICFM is the first step in a process that also includes the removal of male gametes, their treatment and their use in intrauterine artificial insemination or in vitro fertilization techniques.
Translated title of the contribution[Autom. eng. transl.] Analysis of the context of application of technology
Original languageItalian
Pages (from-to)2-15
Number of pages14
JournalQuadreni dell'Italian Journal of Public Health
Publication statusPublished - 2012


  • Infertilità
  • epidemiologia


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