An unusual case showing fatal rupture of a gastric ulcer or gastromalacia? The importance/role of histology for differential diagnosis

Fabio De Giorgio, Vincenzo Lorenzo Pascali, Antonio Gioacchino Spagnolo, Vincenzo Arena, Maria Lodise, Ernesto D'Aloja

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Gastromalacia is the acute autolytic erosion of the gastric wall. It generally occurs postmortem, and it appears as a slimy brownish black region of the wall which occurs principally in the gastric fundus. A 59-year-old woman died in the Emergency Department following a 2-day period of mild abdominal pain, vomiting, and diarrhea. A forensic autopsy was performed which revealed a rupture of the gastric fundus that had caused leakage of gastric content into the abdominal cavity. There was no macroscopic evidence of peritonitis, and the stomach wall adjacent to the rupture site showed marked thinning. The gross appearance was typical of gastromalacia. In contrast, histological observations revealed the presence of an ulcer at the site of perforation and a severe acute inflammatory reaction indicating a robust reaction with an antemortem rupture. © 2014 American Academy of Forensic Sciences.
Original languageEnglish
Pages (from-to)240-242
Number of pages3
JournalJournal of Forensic Sciences
DOIs
Publication statusPublished - 2015

Keywords

  • Abdominal Pain
  • Autolysis
  • Diagnosis

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