In the light of recent findings concerning the importance of intermediate alpha 1-antitrypsin deficiency in the development of chronic liver disease and of hepatocellular carcinoma, we report the case of a 56-year-old woman affected by cirrhosis with significant features of liver cell dysplasia associated with intermediate alpha 1-antitrypsin deficiency (protease inhibitor SZ phenotype). In our paper we emphasize the importance of a precocious diagnosis and identification of individuals carrying the Z allele, also heterozygous.
|Number of pages||7|
|Publication status||Published - 1989|
- Liver Cirrhosis
- Middle Aged
- alpha 1-Antitrypsin
- alpha 1-Antitrypsin Deficiency