Albumin replacement in patients with severe sepsis or septic shock

Massimo Antonelli, Giovanni Tognoni, Pietro Caironi, Gianni Tognoni, Serge Masson, Roberto Fumagalli, Antonio Pesenti, Marilena Romero, Caterina Fanizza, Luisa Caspani, Stefano Faenza, Giacomo Grasselli, Gaetano Iapichino, Vieri Parrini, Gilberto Fiore, Roberto Latini, Luciano Gattinoni

Research output: Contribution to journalArticle

565 Citations (Scopus)


Although previous studies have suggested the potential advantages of albumin administration in patients with severe sepsis, its efficacy has not been fully established.
Original languageEnglish
Pages (from-to)1412-1421
Number of pages10
JournalNew England Journal of Medicine
Publication statusPublished - 2014


  • Aged
  • Albumins
  • Female
  • Humans
  • Isotonic Solutions
  • Male
  • Middle Aged
  • Rehydration Solutions
  • Sepsis
  • Serum Albumin
  • Shock, Septic
  • Survival Rate
  • Treatment Outcome


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