Adalimumab in active ulcerative colitis: a "real-life" observational study

Alessandro Armuzzi; Livia Biancone; Marco Daperno; Alessandra Coli; Daniela Pugliese; Vito Annese; Annalisa Aratari; Sandro Ardizzone; Paola Balestrieri; Fabrizio Bossa; Maria Cappello; Fabiana Castiglione; Michele Cicala; Silvio Danese; Renata D'Incà; Pietro Dulbecco; Giuseppe Feliciangeli; Walter Fries; Stefania Genise; Paolo Gionchetti; Stefano Gozzi; Anna Kohn; Roberto Lorenzetti; Monica Milla; Sara Onali; Ambrogio Orlando; Luigi Giovanni Papparella; Sara Renna; Chiara Ricci; Fernando Rizzello; Raffaello Sostegni; Luisa Guidi; Claudio Papi

doi:10.1016/j.dld.2013.03.018

Adalimumab in active ulcerative colitis: a "real-life" observational study

Alessandro Armuzzi
, Livia Biancone
, Marco Daperno
, Alessandra Coli
, Daniela Pugliese
, Vito Annese
, Annalisa Aratari
, Sandro Ardizzone
, Paola Balestrieri
, Fabrizio Bossa
, Maria Cappello
, Fabiana Castiglione
, Michele Cicala
, Silvio Danese
, Renata D'Incà
, Pietro Dulbecco
, Giuseppe Feliciangeli
, Walter Fries
, Stefania Genise
, Paolo Gionchetti

Stefano Gozzi, Anna Kohn, Roberto Lorenzetti, Monica Milla, Sara Onali, Ambrogio Orlando, Luigi Giovanni Papparella, Sara Renna, Chiara Ricci, Fernando Rizzello, Raffaello Sostegni, Luisa Guidi, Claudio Papi

University of Rome Tor Vergata
Ospedale Mauriziano Umberto I
University of Pisa
Azienda Ospedaliera Careggi
San Filippo Neri Hospital
University of Milan
Universita Campus Bio-Medico di Roma
IRCCS Ospedale Casa Sollievo della Sofferenza - San Giovanni Rotondo (FG)
University of Palermo
University of Naples Federico II
IRCCS Istituto Clinico Humanitas - Rozzano (Milano)
University of Padua
University of Genoa
Macerata Hospital
University of Messina
University of Bologna
IRCCS Policlinico San Donato
San Camillo Hospital
University of Brescia

Research output: Contribution to journal › Article

55 Citations (Scopus)

Abstract

The effectiveness of adalimumab in the treatment of ulcerative colitis is under debate. Although controlled trials have shown that adalimumab is significantly better than placebo, the absolute clinical benefit is modest. We report data on the effectiveness of adalimumab in a cohort of ulcerative colitis patients treated in 22 Italian centres.

Original language	English
Pages (from-to)	738-743
Number of pages	6
Journal	Digestive and Liver Disease
Volume	45
DOIs	https://doi.org/10.1016/j.dld.2013.03.018
Publication status	Published - 2013

Keywords

Adalimumab
Ulcerative colitis
“Real-life” study

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10.1016/j.dld.2013.03.018

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Armuzzi, A., Biancone, L., Daperno, M., Coli, A., Pugliese, D., Annese, V., Aratari, A., Ardizzone, S., Balestrieri, P., Bossa, F., Cappello, M., Castiglione, F., Cicala, M., Danese, S., D'Incà, R., Dulbecco, P., Feliciangeli, G., Fries, W., Genise, S., ... Papi, C. (2013). Adalimumab in active ulcerative colitis: a "real-life" observational study. Digestive and Liver Disease, 45, 738-743. https://doi.org/10.1016/j.dld.2013.03.018

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title = "Adalimumab in active ulcerative colitis: a {"}real-life{"} observational study",

abstract = "The effectiveness of adalimumab in the treatment of ulcerative colitis is under debate. Although controlled trials have shown that adalimumab is significantly better than placebo, the absolute clinical benefit is modest. We report data on the effectiveness of adalimumab in a cohort of ulcerative colitis patients treated in 22 Italian centres.",

keywords = "Adalimumab, Ulcerative colitis, “Real-life” study, Adalimumab, Ulcerative colitis, “Real-life” study",

author = "Alessandro Armuzzi and Livia Biancone and Marco Daperno and Alessandra Coli and Daniela Pugliese and Vito Annese and Annalisa Aratari and Sandro Ardizzone and Paola Balestrieri and Fabrizio Bossa and Maria Cappello and Fabiana Castiglione and Michele Cicala and Silvio Danese and Renata D'Inc{\`a} and Pietro Dulbecco and Giuseppe Feliciangeli and Walter Fries and Stefania Genise and Paolo Gionchetti and Stefano Gozzi and Anna Kohn and Roberto Lorenzetti and Monica Milla and Sara Onali and Ambrogio Orlando and \{Giovanni Papparella\}, Luigi and Sara Renna and Chiara Ricci and Fernando Rizzello and Raffaello Sostegni and Luisa Guidi and Claudio Papi",

year = "2013",

doi = "10.1016/j.dld.2013.03.018",

language = "English",

volume = "45",

pages = "738--743",

journal = "Digestive and Liver Disease",

issn = "1590-8658",

}

Armuzzi, A, Biancone, L, Daperno, M, Coli, A, Pugliese, D, Annese, V, Aratari, A, Ardizzone, S, Balestrieri, P, Bossa, F, Cappello, M, Castiglione, F, Cicala, M, Danese, S, D'Incà, R, Dulbecco, P, Feliciangeli, G, Fries, W, Genise, S, Gionchetti, P, Gozzi, S, Kohn, A, Lorenzetti, R, Milla, M, Onali, S, Orlando, A, Giovanni Papparella, L, Renna, S, Ricci, C, Rizzello, F, Sostegni, R, Guidi, L & Papi, C 2013, 'Adalimumab in active ulcerative colitis: a "real-life" observational study', Digestive and Liver Disease, vol. 45, pp. 738-743. https://doi.org/10.1016/j.dld.2013.03.018

TY - JOUR

T1 - Adalimumab in active ulcerative colitis: a "real-life" observational study

AU - Armuzzi, Alessandro

AU - Biancone, Livia

AU - Daperno, Marco

AU - Coli, Alessandra

AU - Pugliese, Daniela

AU - Annese, Vito

AU - Aratari, Annalisa

AU - Ardizzone, Sandro

AU - Balestrieri, Paola

AU - Bossa, Fabrizio

AU - Cappello, Maria

AU - Castiglione, Fabiana

AU - Cicala, Michele

AU - Danese, Silvio

AU - D'Incà, Renata

AU - Dulbecco, Pietro

AU - Feliciangeli, Giuseppe

AU - Fries, Walter

AU - Genise, Stefania

AU - Gionchetti, Paolo

AU - Gozzi, Stefano

AU - Kohn, Anna

AU - Lorenzetti, Roberto

AU - Milla, Monica

AU - Onali, Sara

AU - Orlando, Ambrogio

AU - Giovanni Papparella, Luigi

AU - Renna, Sara

AU - Ricci, Chiara

AU - Rizzello, Fernando

AU - Sostegni, Raffaello

AU - Guidi, Luisa

AU - Papi, Claudio

PY - 2013

Y1 - 2013

N2 - The effectiveness of adalimumab in the treatment of ulcerative colitis is under debate. Although controlled trials have shown that adalimumab is significantly better than placebo, the absolute clinical benefit is modest. We report data on the effectiveness of adalimumab in a cohort of ulcerative colitis patients treated in 22 Italian centres.

AB - The effectiveness of adalimumab in the treatment of ulcerative colitis is under debate. Although controlled trials have shown that adalimumab is significantly better than placebo, the absolute clinical benefit is modest. We report data on the effectiveness of adalimumab in a cohort of ulcerative colitis patients treated in 22 Italian centres.

KW - Adalimumab

KW - Ulcerative colitis

KW - “Real-life” study

KW - Adalimumab

KW - Ulcerative colitis

KW - “Real-life” study

UR - http://hdl.handle.net/10807/52382

U2 - 10.1016/j.dld.2013.03.018

DO - 10.1016/j.dld.2013.03.018

M3 - Article

SN - 1590-8658

VL - 45

SP - 738

EP - 743

JO - Digestive and Liver Disease

JF - Digestive and Liver Disease

ER -

Adalimumab in active ulcerative colitis: a "real-life" observational study

Abstract

Keywords

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