Abitudini alimentari e melanoma cutaneo: nuove prospettive per la prevenzione?

Translated title of the contribution: [Autom. eng. transl.] Eating habits and cutaneous melanoma: new perspectives for prevention?

Gianluigi Quaranta, Chiara Cadeddu, Gualtiero Ricciardi, Chiara De Waure, Giuseppe La Torre, Mr Gualano, A Jovic Vranes, B Djiankovic

Research output: Contribution to journalConference article


[Autom. eng. transl.] OBJECTIVES: Cutaneous Melanoma (MC) affects about 200,000 subjects each year, of which 46,000 are destined to die due to the disease. The main risk factor is represented by the exposure to ultraviolet radiation, but several publications have turned their attention to the analysis of the impact of eating habits. The purpose of this study is to carry out a systematic review of the works that have investigated the association between eating habits and CD in order to provide useful evidence to decision-makers in Public Health. METHOD: PubMed, OvidSP and Cochrane Library databases were used to identify potentially eligible studies; the research was continued from 1990 to July 2011 and case-control and cohort studies were considered eligible. Following the selection of the works, two researchers independently assessed the quality through the Newcastle-Ottawa Scale (NOS) and extrapolated the data. Odds ratios or related risks were extracted, adjusted for potential confounding factors, for subjects who had taken the highest amounts of different food groups compared to those with the lowest levels of intake. RESULTS: The literature search produced 266 articles of which 15 considered as eligible: 13 were case-control and 2 cohort studies. Eight studies (53.3%) were conducted in Europe, the remaining mainly in the United States. The sample size was variable from 98 to 1,400 for the case-control studies and from 50,757 to 121,700 for the cohort studies. According to the NOS the cohort studies achieved a better score than those in the control case. The studies were remarkably heterogeneous in terms of tools used for the evaluation of dietary habits since, in most cases, non-standardized questionnaires were used. For this reason the combination of data was not considered appropriate and a qualitative summary was carried out. Most studies did not reveal a statistically significant association between food intake and MC. However, one study showed a 46% reduction in the risk of CD with fruit consumption, three a 30-50% reduction with vegetable intake and two a decline of about 35-38% associated with consumption of fruit. fish. CONCLUSIONS: The work highlights the existence of an inverse association between MC risk and intake of fish, vegetables and fruit. However, heterogeneity prevents us from drawing definitive conclusions that would be necessary to set up education and health promotion campaigns aimed at the primary prevention of CD.
Translated title of the contribution[Autom. eng. transl.] Eating habits and cutaneous melanoma: new perspectives for prevention?
Original languageItalian
Pages (from-to)263-263
Number of pages1
Publication statusPublished - 2013
Event45° Congresso Nazionale SItI - Cagliari
Duration: 3 Oct 20126 Oct 2012


  • Dieta
  • Melanoma


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