A Rare Case of Ectopic Adrenocorticotropic Hormone Syndrome Caused by a Metastatic Neuroendocrine Tumor of the Pancreas Detected by 68Ga-DOTANOC and 18F-FDG PET/CT

Andrea Giaccari, Guido Rindi, Vittoria Rufini, Giorgio Treglia, Enrica Salomone, Gianluigi Petrone

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15 Citations (Scopus)

Abstract

We report a rare case of ectopic adrenocorticotropic hormone (ACTH) syndrome caused by a metastatic neuroendocrine tumor (NET) of the pancreas detected by PET/CT using different tracers. A 43-year-old female patient with Cushing syndrome (CS) by suspected ectopic ACTH secretion underwent a Ga-DOTANOC and a F-FDG PET/CT. Both these functional imaging techniques revealed increased tracer uptake in a pancreatic mass and multiple liver metastases. Histology showed the presence of a mildly differentiated pancreatic NET. Ga-DOTANOC PET/CT may be a useful functional imaging method, complementary to F-FDG PET/CT, in detecting ACTH-secreting pancreatic NETs.
Original languageEnglish
Pages (from-to)N/A-N/A
Number of pages3
JournalClinical Nuclear Medicine
Volume2013
DOIs
Publication statusPublished - 2013

Keywords

  • CUSHING ECTOPICO
  • ECTOPIC ACTH SYNDROME
  • F-FDG
  • Ga-DOTANOC
  • NEUROENDOCRINE TUMORS
  • TUMORI ENUROENDOCRINI

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