A critical review of the efficacy and safety in the use of low-molecular-weight heparin in acute ST-elevation myocardial infarction: a Bayesan approach

E Buccelletti, C Spadaccio, M Chello, Davide Marsiliani, Annarita Carroccia, P Iacomini, G Calabrò, Nicolo' Gentiloni Silveri, Francesco Franceschi

Research output: Contribution to journalArticle

Abstract

ST segment elevation myocardial infarction (STEMI) is an important risk factor of death worldwide. Significant clinical research has been done to assess ideal reperfusion strategies in the setting of STEMI, including the role of the antithrombin agents: unfractionated heparin (UFH) and low molecular weight heparin (LMWH). Given the evidence that LMWH may be safer than UFH in the treatment of other thrombotic disorders, its role in the management of STEMI needs to be more defined.
Original languageEnglish
Pages (from-to)701-710
Number of pages10
JournalEuropean Review for Medical and Pharmacological Sciences
Volume15
Publication statusPublished - 2011

Keywords

  • Anticoagulants
  • Bayes Theorem
  • Hemorrhage
  • Heparin, Low-Molecular-Weight
  • Humans
  • Models, Statistical
  • Myocardial Infarction
  • Randomized Controlled Trials as Topic

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