68Ga-DOTATOC PET/CT in Thyroid Metastases of Lung Carcinoid.

Lucia Leccisotti; Margherita Lorusso; Elisa Giannetta; Andrea M. Isidori; Vittoria Rufini

doi:10.1097/RLU.0000000000002331

68Ga-DOTATOC PET/CT in Thyroid Metastases of Lung Carcinoid.

Lucia Leccisotti^*, Margherita Lorusso, Elisa Giannetta, Andrea M. Isidori, Vittoria Rufini

^*Corresponding author

University of Rome La Sapienza

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Abstract

We report the case of a 43-year-old man with a history of lung carcinoid and a recent detection of thyroid nodules by ultrasound. The cytological analysis raised the suspicion of medullary thyroid carcinoma; however, calcitonin and carcinoembryonic antigen levels were in reference range. Considering the previous diagnosis of lung carcinoid, the patient underwentwhole-body 68Ga-DOTATOCPET/CT. The images showed focal radiopharmaceutical uptake in both thyroid lobes. After thyroidectomy, the histology and immunohistochemistry (negative for calcitonin and positive for chromogranin A) confirmed the neuroendocrine origin of the thyroid nodules, possibly referable to previous lung carcinoid.

Original language	English
Pages (from-to)	e492-e494
Number of pages	3
Journal	Clinical Nuclear Medicine
Volume	2018
DOIs	https://doi.org/10.1097/RLU.0000000000002331
Publication status	Published - 2018

Keywords

thyroid metastases, neuroendocrine tumor, 68Ga-DOTATOC, PET/CT, somatostatin receptor

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title = "68Ga-DOTATOC PET/CT in Thyroid Metastases of Lung Carcinoid.",

abstract = "We report the case of a 43-year-old man with a history of lung carcinoid and a recent detection of thyroid nodules by ultrasound. The cytological analysis raised the suspicion of medullary thyroid carcinoma; however, calcitonin and carcinoembryonic antigen levels were in reference range. Considering the previous diagnosis of lung carcinoid, the patient underwentwhole-body 68Ga-DOTATOCPET/CT. The images showed focal radiopharmaceutical uptake in both thyroid lobes. After thyroidectomy, the histology and immunohistochemistry (negative for calcitonin and positive for chromogranin A) confirmed the neuroendocrine origin of the thyroid nodules, possibly referable to previous lung carcinoid.",

keywords = "thyroid metastases, neuroendocrine tumor, 68Ga-DOTATOC, PET/CT, somatostatin receptor, thyroid metastases, neuroendocrine tumor, 68Ga-DOTATOC, PET/CT, somatostatin receptor",

author = "Lucia Leccisotti and Margherita Lorusso and Elisa Giannetta and Isidori, {Andrea M.} and Vittoria Rufini",

year = "2018",

doi = "10.1097/RLU.0000000000002331",

language = "English",

volume = "2018",

pages = "e492--e494",

journal = "Clinical Nuclear Medicine",

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T1 - 68Ga-DOTATOC PET/CT in Thyroid Metastases of Lung Carcinoid.

AU - Leccisotti, Lucia

AU - Lorusso, Margherita

AU - Giannetta, Elisa

AU - Isidori, Andrea M.

AU - Rufini, Vittoria

PY - 2018

Y1 - 2018

N2 - We report the case of a 43-year-old man with a history of lung carcinoid and a recent detection of thyroid nodules by ultrasound. The cytological analysis raised the suspicion of medullary thyroid carcinoma; however, calcitonin and carcinoembryonic antigen levels were in reference range. Considering the previous diagnosis of lung carcinoid, the patient underwentwhole-body 68Ga-DOTATOCPET/CT. The images showed focal radiopharmaceutical uptake in both thyroid lobes. After thyroidectomy, the histology and immunohistochemistry (negative for calcitonin and positive for chromogranin A) confirmed the neuroendocrine origin of the thyroid nodules, possibly referable to previous lung carcinoid.

AB - We report the case of a 43-year-old man with a history of lung carcinoid and a recent detection of thyroid nodules by ultrasound. The cytological analysis raised the suspicion of medullary thyroid carcinoma; however, calcitonin and carcinoembryonic antigen levels were in reference range. Considering the previous diagnosis of lung carcinoid, the patient underwentwhole-body 68Ga-DOTATOCPET/CT. The images showed focal radiopharmaceutical uptake in both thyroid lobes. After thyroidectomy, the histology and immunohistochemistry (negative for calcitonin and positive for chromogranin A) confirmed the neuroendocrine origin of the thyroid nodules, possibly referable to previous lung carcinoid.

KW - thyroid metastases, neuroendocrine tumor, 68Ga-DOTATOC, PET/CT, somatostatin receptor

UR - http://hdl.handle.net/10807/153421

U2 - 10.1097/RLU.0000000000002331

DO - 10.1097/RLU.0000000000002331

M3 - Article

SN - 0363-9762

VL - 2018

SP - e492-e494

JO - Clinical Nuclear Medicine

JF - Clinical Nuclear Medicine

ER -

68Ga-DOTATOC PET/CT in Thyroid Metastases of Lung Carcinoid.

Abstract

Keywords

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