68Ga-DOTATOC PET/CT in Thyroid Metastases of Lung Carcinoid

Lucia Leccisotti; Margherita Lorusso; Elisa Giannetta; Andrea M Isidori; Vittoria Rufini

doi:10.1097/RLU.0000000000002331

68Ga-DOTATOC PET/CT in Thyroid Metastases of Lung Carcinoid

Lucia Leccisotti^*
, Margherita Lorusso
, Elisa Giannetta
, Andrea M Isidori
, Vittoria Rufini

^*Corresponding author

University of Rome La Sapienza

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

We report the case of a 43-year-old man with a history of lung carcinoid and a recent detection of thyroid nodules by ultrasound. The cytological analysis raised the suspicion of medullary thyroid carcinoma; however, calcitonin and carcinoembryonic antigen levels were in reference range. Considering the previous diagnosis of lung carcinoid, the patient underwentwhole-body 68Ga-DOTATOCPET/CT. The images showed focal radiopharmaceutical uptake in both thyroid lobes. After thyroidectomy, the histology and immunohistochemistry (negative for calcitonin and positive for\r\nchromogranin A) confirmed the neuroendocrine origin of the thyroid nodules, possibly referable to previous lung carcinoid.

Original language	English
Pages (from-to)	e492-e494
Number of pages	3
Journal	Clinical Nuclear Medicine
Volume	2018
Issue number	43(12)
DOIs	https://doi.org/10.1097/RLU.0000000000002331
Publication status	Published - 2018

All Science Journal Classification (ASJC) codes

Radiology Nuclear Medicine and imaging

Keywords

68Ga-DOTATOC PET/CT
neuroendocrine tumor
somatostatin receptor
thyroid metastases

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10.1097/RLU.0000000000002331

Cite this

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title = "68Ga-DOTATOC PET/CT in Thyroid Metastases of Lung Carcinoid",

abstract = "We report the case of a 43-year-old man with a history of lung carcinoid and a recent detection of thyroid nodules by ultrasound. The cytological analysis raised the suspicion of medullary thyroid carcinoma; however, calcitonin and carcinoembryonic antigen levels were in reference range. Considering the previous diagnosis of lung carcinoid, the patient underwentwhole-body 68Ga-DOTATOCPET/CT. The images showed focal radiopharmaceutical uptake in both thyroid lobes. After thyroidectomy, the histology and immunohistochemistry (negative for calcitonin and positive for\textbackslash{}r\textbackslash{}nchromogranin A) confirmed the neuroendocrine origin of the thyroid nodules, possibly referable to previous lung carcinoid.",

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AU - Leccisotti, Lucia

AU - Lorusso, Margherita

AU - Giannetta, Elisa

AU - Isidori, Andrea M

AU - Rufini, Vittoria

PY - 2018

Y1 - 2018

N2 - We report the case of a 43-year-old man with a history of lung carcinoid and a recent detection of thyroid nodules by ultrasound. The cytological analysis raised the suspicion of medullary thyroid carcinoma; however, calcitonin and carcinoembryonic antigen levels were in reference range. Considering the previous diagnosis of lung carcinoid, the patient underwentwhole-body 68Ga-DOTATOCPET/CT. The images showed focal radiopharmaceutical uptake in both thyroid lobes. After thyroidectomy, the histology and immunohistochemistry (negative for calcitonin and positive for\r\nchromogranin A) confirmed the neuroendocrine origin of the thyroid nodules, possibly referable to previous lung carcinoid.

AB - We report the case of a 43-year-old man with a history of lung carcinoid and a recent detection of thyroid nodules by ultrasound. The cytological analysis raised the suspicion of medullary thyroid carcinoma; however, calcitonin and carcinoembryonic antigen levels were in reference range. Considering the previous diagnosis of lung carcinoid, the patient underwentwhole-body 68Ga-DOTATOCPET/CT. The images showed focal radiopharmaceutical uptake in both thyroid lobes. After thyroidectomy, the histology and immunohistochemistry (negative for calcitonin and positive for\r\nchromogranin A) confirmed the neuroendocrine origin of the thyroid nodules, possibly referable to previous lung carcinoid.

KW - 68Ga-DOTATOC PET/CT

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KW - somatostatin receptor

KW - thyroid metastases

KW - 68Ga-DOTATOC PET/CT

KW - neuroendocrine tumor

KW - somatostatin receptor

KW - thyroid metastases

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68Ga-DOTATOC PET/CT in Thyroid Metastases of Lung Carcinoid

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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