68Ga-DOTATOC PET/CT in Thyroid Metastases of Lung Carcinoid

Lucia Leccisotti; Elisa Giannetta; Andrea M. Isidori; Vittoria Rufini

doi:10.1097/RLU.0000000000002331

68Ga-DOTATOC PET/CT in Thyroid Metastases of Lung Carcinoid

Lucia Leccisotti^*, Elisa Giannetta, Andrea M. Isidori, Vittoria Rufini

^*Corresponding author

University of Rome La Sapienza

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

We report the case of a 43-year-old man with a history of lung carcinoid and a recent detection of thyroid nodules by ultrasound. The cytological analysis raised the suspicion of medullary thyroid carcinoma; however, calcitonin and carcinoembryonic antigen levels were in reference range. Considering the previous diagnosis of lung carcinoid, the patient underwentwhole-body 68Ga-DOTATOCPET/CT. The images showed focal radiopharmaceutical uptake in both thyroid lobes. After thyroidectomy, the histology and immunohistochemistry (negative for calcitonin and positive for chromogranin A) confirmed the neuroendocrine origin of the thyroid nodules, possibly referable to previous lung carcinoid.

Original language	English
Pages (from-to)	e492-e494
Number of pages	3
Journal	Clinical Nuclear Medicine
Volume	2018
DOIs	https://doi.org/10.1097/RLU.0000000000002331
Publication status	Published - 2018

Keywords

68Ga-DOTATOC PET/CT
neuroendocrine tumor
somatostatin receptor
thyroid metastases

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10.1097/RLU.0000000000002331

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title = "68Ga-DOTATOC PET/CT in Thyroid Metastases of Lung Carcinoid",

abstract = "We report the case of a 43-year-old man with a history of lung carcinoid and a recent detection of thyroid nodules by ultrasound. The cytological analysis raised the suspicion of medullary thyroid carcinoma; however, calcitonin and carcinoembryonic antigen levels were in reference range. Considering the previous diagnosis of lung carcinoid, the patient underwentwhole-body 68Ga-DOTATOCPET/CT. The images showed focal radiopharmaceutical uptake in both thyroid lobes. After thyroidectomy, the histology and immunohistochemistry (negative for calcitonin and positive for chromogranin A) confirmed the neuroendocrine origin of the thyroid nodules, possibly referable to previous lung carcinoid.",

keywords = "68Ga-DOTATOC PET/CT, neuroendocrine tumor, somatostatin receptor, thyroid metastases, 68Ga-DOTATOC PET/CT, neuroendocrine tumor, somatostatin receptor, thyroid metastases",

author = "Lucia Leccisotti and Elisa Giannetta and Isidori, {Andrea M.} and Vittoria Rufini",

year = "2018",

doi = "10.1097/RLU.0000000000002331",

language = "English",

volume = "2018",

pages = "e492--e494",

journal = "Clinical Nuclear Medicine",

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T1 - 68Ga-DOTATOC PET/CT in Thyroid Metastases of Lung Carcinoid

AU - Leccisotti, Lucia

AU - Giannetta, Elisa

AU - Isidori, Andrea M.

AU - Rufini, Vittoria

PY - 2018

Y1 - 2018

N2 - We report the case of a 43-year-old man with a history of lung carcinoid and a recent detection of thyroid nodules by ultrasound. The cytological analysis raised the suspicion of medullary thyroid carcinoma; however, calcitonin and carcinoembryonic antigen levels were in reference range. Considering the previous diagnosis of lung carcinoid, the patient underwentwhole-body 68Ga-DOTATOCPET/CT. The images showed focal radiopharmaceutical uptake in both thyroid lobes. After thyroidectomy, the histology and immunohistochemistry (negative for calcitonin and positive for chromogranin A) confirmed the neuroendocrine origin of the thyroid nodules, possibly referable to previous lung carcinoid.

AB - We report the case of a 43-year-old man with a history of lung carcinoid and a recent detection of thyroid nodules by ultrasound. The cytological analysis raised the suspicion of medullary thyroid carcinoma; however, calcitonin and carcinoembryonic antigen levels were in reference range. Considering the previous diagnosis of lung carcinoid, the patient underwentwhole-body 68Ga-DOTATOCPET/CT. The images showed focal radiopharmaceutical uptake in both thyroid lobes. After thyroidectomy, the histology and immunohistochemistry (negative for calcitonin and positive for chromogranin A) confirmed the neuroendocrine origin of the thyroid nodules, possibly referable to previous lung carcinoid.

KW - 68Ga-DOTATOC PET/CT

KW - neuroendocrine tumor

KW - somatostatin receptor

KW - thyroid metastases

KW - 68Ga-DOTATOC PET/CT

KW - neuroendocrine tumor

KW - somatostatin receptor

KW - thyroid metastases

UR - http://hdl.handle.net/10807/133657

U2 - 10.1097/RLU.0000000000002331

DO - 10.1097/RLU.0000000000002331

M3 - Article

SN - 0363-9762

VL - 2018

SP - e492-e494

JO - Clinical Nuclear Medicine

JF - Clinical Nuclear Medicine

ER -

68Ga-DOTATOC PET/CT in Thyroid Metastases of Lung Carcinoid

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Keywords

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