2-Substituted 3-Arylindoles Through Palladium-Catalyzed Arylative Cyclization of 2-Alkynyltrifluoroacetanilides with Arylboronic Acids under Oxidative Conditions

Antonio Arcadi; Sandro Cacchi; Giancarlo Fabrizi; Antonella Goggiamani; Antonia Iazzetti; Fabio Marinelli

doi:10.1039/c2ob27125g

2-Substituted 3-Arylindoles Through Palladium-Catalyzed Arylative Cyclization of 2-Alkynyltrifluoroacetanilides with Arylboronic Acids under Oxidative Conditions

Antonio Arcadi^*, Sandro Cacchi, Giancarlo Fabrizi, Antonella Goggiamani^*, Antonia Iazzetti, Fabio Marinelli

^*Corresponding author

Research output: Contribution to journal › Article

Abstract

Free NH 2-substituted 3-arylindoles have been prepared usually in good to high yields through the palladium-catalyzed reaction of readily available 2-alkynyltrifluoroacetanilides with arylboronic acids under oxidative conditions. The reaction tolerates a variety of useful functional groups both in the arylboronic acid and in the alkyne, including chloro, formyl, and ester groups.

Original language	English
Pages (from-to)	no-no
Journal	CHEM INFORM
Volume	44
DOIs	https://doi.org/10.1039/c2ob27125g
Publication status	Published - 2013

Keywords

inglese

Access to Document

10.1039/c2ob27125g

Cite this

@article{61f9d6557084488aba3643af90bfdb9d,

title = "2-Substituted 3-Arylindoles Through Palladium-Catalyzed Arylative Cyclization of 2-Alkynyltrifluoroacetanilides with Arylboronic Acids under Oxidative Conditions",

abstract = "Free NH 2-substituted 3-arylindoles have been prepared usually in good to high yields through the palladium-catalyzed reaction of readily available 2-alkynyltrifluoroacetanilides with arylboronic acids under oxidative conditions. The reaction tolerates a variety of useful functional groups both in the arylboronic acid and in the alkyne, including chloro, formyl, and ester groups.",

keywords = "inglese, inglese",

author = "Antonio Arcadi and Sandro Cacchi and Giancarlo Fabrizi and Antonella Goggiamani and Antonia Iazzetti and Fabio Marinelli",

year = "2013",

doi = "10.1039/c2ob27125g",

language = "English",

volume = "44",

pages = "no--no",

journal = "CHEM INFORM",

issn = "0931-7597",

publisher = "Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: [email protected], INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328",

}

TY - JOUR

T1 - 2-Substituted 3-Arylindoles Through Palladium-Catalyzed Arylative Cyclization of 2-Alkynyltrifluoroacetanilides with Arylboronic Acids under Oxidative Conditions

AU - Arcadi, Antonio

AU - Cacchi, Sandro

AU - Fabrizi, Giancarlo

AU - Goggiamani, Antonella

AU - Iazzetti, Antonia

AU - Marinelli, Fabio

PY - 2013

Y1 - 2013

N2 - Free NH 2-substituted 3-arylindoles have been prepared usually in good to high yields through the palladium-catalyzed reaction of readily available 2-alkynyltrifluoroacetanilides with arylboronic acids under oxidative conditions. The reaction tolerates a variety of useful functional groups both in the arylboronic acid and in the alkyne, including chloro, formyl, and ester groups.

AB - Free NH 2-substituted 3-arylindoles have been prepared usually in good to high yields through the palladium-catalyzed reaction of readily available 2-alkynyltrifluoroacetanilides with arylboronic acids under oxidative conditions. The reaction tolerates a variety of useful functional groups both in the arylboronic acid and in the alkyne, including chloro, formyl, and ester groups.

KW - inglese

UR - http://hdl.handle.net/10807/200814

U2 - 10.1039/c2ob27125g

DO - 10.1039/c2ob27125g

M3 - Article

SN - 0931-7597

VL - 44

SP - no-no

JO - CHEM INFORM

JF - CHEM INFORM

ER -

2-Substituted 3-Arylindoles Through Palladium-Catalyzed Arylative Cyclization of 2-Alkynyltrifluoroacetanilides with Arylboronic Acids under Oxidative Conditions

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this